

Figure 5 shows the development of spinal cord in embryonal size of 5.5 mm, 18.3 mm and 26.3 mm. Premature spinal cord is visualized on the back, which is compatible with 3D image on Figure 3. Figure 4 is macrographic images of an aborted specimen taken just after abortion. Early neural tube and premature spinal cord are successfully demonstrated in a small embryo. Figures 2 and 3 show 5.5 mm long embryo with yolk sac at 6 weeks of gestation and 18.3 mm CRL-embryo at 8 weeks of gestation respectively, depicted by using the most up-dated 3D equipment with high-frequency transvaginal transducer (Voluson ® E8 with 12 MHz/256 element vaginal probe, GE Healthcare, Milwaukee, USA). Demonstration of small embryo less than 10 mm of greatest length has been difficult and not visualized in detail. Figure 1 shows a gestational sac at four weeks of gestation and the yolk sac visualization at five weeks of gestation. Recent introduction of three-dimensional and four-dimensional ultrasounds combined with the transvaginal approach has produced more objective and accurate information on embryonal and early fetal development.
